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Randy Dockens Selected Research

BMS 708163

11/2015Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.
1/2013A contrast in safety, pharmacokinetics and pharmacodynamics across age groups after a single 50 mg oral dose of the γ-secretase inhibitor avagacestat.
11/2012Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease.
10/2012A placebo-controlled, multiple ascending dose study to evaluate the safety, pharmacokinetics and pharmacodynamics of avagacestat (BMS-708163) in healthy young and elderly subjects.

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Randy Dockens Research Topics

Disease

4Alzheimer Disease (Alzheimer's Disease)
11/2015 - 10/2012
2Skin Neoplasms (Skin Cancer)
11/2015 - 11/2012
2Cognitive Dysfunction
11/2015 - 01/2013
1Lymphadenopathy
01/2022
1Cellulitis
01/2022
1Pharyngitis (Sore Throat)
01/2022
1Atrophy
11/2015
1Dementia (Dementias)
11/2015
1Disease Progression
11/2015
1Multiple Endocrine Neoplasia Type 2a (MEN 2)
10/2012
1Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
06/2009

Drug/Important Bio-Agent (IBA)

4BMS 708163IBA
11/2015 - 10/2012
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
11/2015 - 11/2012
1deucravacitinibIBA
01/2022
1Biomarkers (Surrogate Marker)IBA
11/2015
1Glucose (Dextrose)FDA LinkGeneric
11/2012
1Adrenocorticotropic Hormone (ACTH)FDA Link
06/2009